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Green and sustainable metrics: Charting the course for green-by-design small molecule API synthesis

Elsevier
Publication Date
Authors
Author Name
Harrison B. Rose
Author Name
Birgit Kosjek
Author Name
Brittany M. Armstrong
Author Name
Sandra A. Robaire
  • A Green-by-Design strategy for sustainable manufacturing relies on the consistent application of metrics and targets.
  • Existing tools set targets and/or score processes using a range of methodologies and structural or manufacturing data.
  • The Streamlined PMI-LCA Tool facilitates routine process scoring and prioritization of development tasks with minimal data required.
  • The Green-by-Design development strategy for the MK-7264 active pharmaceutical ingredient is outlined here.
Link
https://doi.org/10.1016/j.crgsc.2022.100324
Source
Current Research in Green and Sustainable Chemistry
Additional Guidance
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