Chemo- and Regioselective Aqueous Phase, Co-Acid Free Nitration of Aromatics Using Traditional and Nontraditional Activation Methods
Electrophilic aromatic nitrations are used for the preparation of a variety of synthetic products including dyes, agrochemicals, high energy materials, and pharmaceuticals. Moreover, nitro compounds can be used as intermediates and easily reduced to products such as anilines, that are important feedstock in a broad range of syntheses. Traditional nitration methods use highly acidic and corrosive mixed acid systems which present a number of drawbacks.