Regioselective Biocatalytic De-O-Acetylation of Tetraacetyl Thioglycosides
Carbohydrate mimetics play vital roles in various cell-mediated processes due to their structural resemblance to natural sugars, yet they exhibit distinct properties. Thioglycosides, in which an exocyclic oxygen atom is replaced by sulfur, are recognized as key building blocks in the preparation of glycans and the development of novel monosaccharides. These compounds serve as valuable intermediates in carbohydrate chemistry, being widely utilized in sequential glycosylation strategies for oligosaccharide synthesis.