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on water synthesis

Green Synthesis of New Peptide Triazoles with Potential Activity Against Protease-Activated Receptor 2 (PAR2)

Protease-activated receptor 2 (PAR2) is a G-protein-coupled receptor critical in regulating inflammation, pain, and physiological functions such as wound healing and epithelial barrier integrity. Chronic PAR2 activation contributes to numerous inflammatory and immune diseases, including inflammatory bowel disease (IBD), asthma, and arthritis, and plays a role in tumor progression by promoting proliferation, angiogenesis, and metastasis.