The Acid-Base Selection Tool developed by the ACS Green Chemistry Institute Pharmaceutical Roundtable aims to enable scientists across industry and academia to choose more sustainable acids and bases. The Acid-Base Tool contains over 200 acids and bases which the user can filter by parameters including pKa (in water or acetonitrile), functional groups, melting point, and boiling point.
Produced by the medicinal chemistry focus team of the ACS GCI Pharmaceutical Roundtable, this quick tips guide covers purification, solvent selection, reagents, energy, and resources to make medicinal chemistry more sustainable.
The reagent guides purpose is to encourage chemists to choose a ‘greener’ choice of reaction conditions. The guides aim to achieve this by providing transparency through the use of Venn diagrams in addition to improving understanding by discussion and up to date references.
In line with the green chemistry roundtables core values, these guides aim to assist chemists in making informed decisions when picking the most sustainable reagent for any transformation at hand.