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Biological Sciences

Improvement of Cell-Liposome Interaction for Photodynamic Therapy

Photodynamic therapy (PDT) is a therapeutic alternative for treating several pathologies, from microbial infections to cancer. PDT involves applying a photosensitizer (PS) that interacts with light in an appropriate wavelength, absorbing its energy and going from the basal to the excited singlet state. This excited state can experience intersystem crossing to the excited triplet state (3PS*). 3PS* can generate reactive oxygen species that induce injury and trigger cell death.