Second-generation surfactant that improves the solubility of organic compounds in water. The second generation surfactant, TPGS-750M, allows some organic reactions to be carried out in an aqueous system by improving the solubility of organic compounds in water. This surfactant is composed of safe, inexpensive ingredients and only a small concentration is required for effectiveness. After the reaction, the surfactant can be recovered and reused with minor deactiviation. Organic solvents are traditionally used for organic reactions because they are not soluble in water. These organic solvents are usually toxic, volatile, and flammible, making up the majority of the world's chemical waste. This product can be purchased from Sigma-Aldrich.
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https://lipshutz.chem.ucsb.edu/research
University of California, Santa Barbara Professor Bruce H. Lipshutz