Tool Owner
The EPI (Estimation Programs Interface) Suite™ is a suite of Windows-based programs developed by the EPA in collaboration with Syracuse Research Corp. (SRC). It provides estimations for a variety of physical, chemical, and environmental fate properties using a unified input format. The suite includes the following estimation programs:
- KOWWIN™: Estimates the octanol-water partition coefficient (log KOW) of chemicals using an atom/fragment contribution method.
- AOPWIN™: Estimates gas-phase reaction rates between chemicals and hydroxyl radicals, a prevalent atmospheric oxidant.
- HENRYWIN™: Calculates Henry's Law constant (air/water partition coefficient) using group and bond contribution methods.
- MPBWIN™: Estimates melting point, boiling point, and vapor pressure of organic chemicals using multiple techniques.
- BIOWIN™: Predicts aerobic and anaerobic biodegradability of organic chemicals using different models.
- BioHCwin: Estimates biodegradation half-life for compounds containing carbon and hydrogen.
- KOCWIN™: Estimates organic carbon-normalized sorption coefficient for soil and sediment.
- WSKOWWIN™: Estimates octanol-water partition coefficient using KOWWIN™ and then predicts chemical water solubility with applicable correction factors.
- WATERNT™: Estimates water solubility using a "fragment constant" method.
- BCFBAF™: Estimates fish bioconcentration factor (BCF) and bioaccumulation factor (BAF), incorporating metabolism predictions and estimates for three trophic levels.
- HYDROWIN™: Estimates aqueous hydrolysis rate constants and half-lives for various chemical classes.
- KOAWIN: Estimates octanol/air partition coefficient (KOA) using the ratio of octanol/water partition coefficient (KOW) and dimensionless Henry's Law Constant (KAW).
- AEROWIN™: Estimates airborne substance sorption to particulates.
- WVOLWIN™: Estimates volatilization rate and half-life of chemicals from rivers and lakes.
- STPWIN™: Predicts removal of chemicals in activated sludge-based sewage treatment plants.
- LE3EPI™: Uses a level III multimedia fugacity model to predict chemical partitioning among air, soil, sediment, and water under steady-state conditions.
- ECOSAR™: Estimates aquatic toxicity of industrial chemicals to fish, aquatic invertebrates, and green algae, with limited predictions for other species.
EPI Suite™ supports various Windows versions, and its underlying methods and equations are documented in peer-reviewed technical journals. It serves as a screening-level tool and is recommended for use when measured values are not available or acceptable.