Ensitrelvir fumarate is an orally active antiviral compound that inhibits the SARS-CoV-2 3CL protease, blocking viral replication. As a small-molecule therapeutic, it is used in the development of COVID-19 treatments and related antiviral research.
2-Hydroxy-2-phenyl-acetaldehyde is an aromatic α-hydroxy aldehyde commonly used as an intermediate in organic synthesis. With its reactive aldehyde and hydroxyl functional groups, it serves as a valuable building block for producing pharmaceuticals, fine chemicals, fragrance compounds, and other specialty molecules.
Thailanstatin A is a potent natural product isolated from Burkholderia thailandensis MSMB43. It functions as an ultra-potent inhibitor of eukaryotic RNA splicing by binding to the SF3b subunit of the U2 snRNA subcomplex of the spliceosome. This mechanism results in low-nanomolar to sub-nanomolar IC50 values across various human cancer cell lines, including DU-145, NCI-H232A, MDA-MB-231, and SKOV-3.
Calicheamicin is a highly potent enediyne antitumor antibiotic from Micromonospora echinospora, which cleaves DNA via sequence-specific double-strand breaks. It is employed as the cytotoxic payload in antibody–drug conjugates (ADCs) such as gemtuzumab ozogamicin and inotuzumab ozogamicin for targeted leukemia treatment.
Sulfadimethoxine sodium (Sulphadimethoxine sodium) is a sulfonamide antibiotic used to treat many infections.