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Bulk Chemicals

Bioforge™

AI-engineeered enzymes for the production of chemicals without fermentation. This company uses AI to engineer enzymes and metal catalysts that do not require fermentation, allowing for the production of molecules at room temperature without toxins and waste. This process uses safe feedstocks, such as sugars, air, and carbon dioxide. It is also scalable and cost efficient. This process also eliminates fermentation, costly immobilization, air emissions, and wastewater emissions. Their factory, Bioforge™, produces one ton of product per ton of feedstock.

BioEstolide™ Synthetic Oil

Renewable and biodegradable oils. Estolides are oligomeric fatty acid esters that can be a bio-based alternative to conventional motor oils and industrial lubricants. This alternative avoids permanent damage to water bodies and reduces greenhouse gas emissions by 90%. Estolides are also biodegradable.

4-Aminodiphenylamine (4-ADPA)

Synthetic methodology for the development of 4-ADPA. 4-Aminodiphenylamine (4-ADPA) is a key building block for rubber preservatives. Many aromatic amines are made with halogenated reagents, especially those containing chlorine. The Eastman Chemical Company's previous production of 4-ADPA is based on the chlorination of benzene. This process produced aqueous waste with high levels of inorganic salts that are difficult and expensive to treat. This process also required the storage and handling of large quantities of chlorine gas, which is hazardous to human health.

Safer, Sustainable, Biodegradable, Solid-State Chemistry for Treat Cooling Water Systems

Solid chemistry water treatment. Solid chemistry replaces the heavy, hazardous drums of liquid chemistry used in water treatment. Solid chemistry eliminates the splashing and spilling of liquids, making delivery safer, cleaner, and easier. This technology is more cost-effective as it reduces shipping costs and eliminates expensive storage constraints and disposal fees. The process is also sustainable as it is composed of only biodegradable materials and eliminates dangerous spills and contributions to landfills.

End-of-Life Tires as a Feedstock to Produce Consistent, High Quality Carbon Blacks

Upcycled carbon black from end-of-life tires. Over 1.5 billion end-of-life tires enter the global waste stream annually. This process upcycles end-of-life tires to produce carbon black and tire pyrolytic oil and gas, reducing oil use and carbon dioxide emissions. These carbon blacks are a sustainable, one-to-one replacement for ASTM furnace carbon blacks. The process consists of 5 stages: steel removal, carbonization, de-agglomeration, pelletizing, and drying.

Enzymicals AG Enzymes

Enzymes and chemicals as chiral building blocks, intermediates, specialty chemicals, and recombinant enzymes. This company uses customized chemical synthesis and biocatalytic conversion to produce enzymes and chemicals as chiral building blocks, intermediates, specialty chemicals, and recombinant enzymes. These enzymes are suitable for research and development, diagnostics, and industrial production. Custom enzymes reduce complex synthesis processes into a single biocatalytic step, allowing for operation in milder conditions, product selectivity, and lower physiological toxicity.

Innosyn's Flow Chemistry

Biocatalysis, chemocatalysis, flow chemistry, crystallization, and photochemistry for the development of fine chemicals. Biocatalysis has high selectivity. Chemocatalysis enables efficient, customized synthesis of complex molecules while reducing waste. Flow chemistry allows for control of extreme reaction conditions and hazardous reactants. Due to its superior mass and heat transfer ability, flow chemistry has easy quality control and higher production. This company developed 3D metal-printed flow reactors and mixers using selective laser melting.

Flow Chemistry Reactors

Glass, metal, and ceramic continuous flow reactors and systems. Flow chemistry reactors are more efficient than traditional batch reactors. Flow chemistry reactors have more efficient heat transfer and temperature control due to rapid diffusion and high surface area-to-volume ratios. Increased efficiency allows for more production with less energy waste. Better control over temperature, reaction time, flow, pumped volumes, and pressure enables better control over hazardous materials, improving safety.

High-Purity Glucaric Acid Prodcution through Microbial Fermentation

Lactones, salts, crystals, and other forms of high-purity glucaric acid through fermentation using microbes from biomass. kalion Inc. uses patented microbes from biomass through synthetic biological processes to produce lactones, salts, crystals, and other forms of high-purity glucaric acid through fermentation. Glucaric acid can replace phosphates and chelating agents in detergents and waste treatment. The traditional use of phosphates and chelating agents may include eutrophication, which may interfere with the removal and treatment of toxic metals.

Coflore®

Continuous flow reactors and continuous flow chemicals plays for fine chemical and pharmaceutical industries. This process reduces the amount of solvent required by improving heat transfer. It also enables controlling conditions to maximize conversion without risking competitive or consecutive reactions. Using less solvent and fewer impurities also reduces waste and disposal costs. Using smaller continuous reactors reduces the energy required for heating and cooling. Continuous processes also operate at a steady state, simplifying management. 

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