Design

First-generation surface display technology for better performing enzymes. This technology allows enzymes to be displayed on the outer membrane of bacteria, generating faster results in the screening of binding partners, inhibitors, and optimized enzymes. This technology makes the purification of enzymes simpler and cheaper as it only requires centrifugation and filtration. 

Medical sterilization of sensitive tissues using supercritical carbon dioxide, peracetic acid, and water. Traditional sterilization techniques, such as ethylene oxide and gamma radiation, eliminate bacteria and bacterial endospores while causing severe damage to the tissue. Ethylene oxide can cause mutations and cancer, and gamma radiation can penetrate and damage cells. This process serves as an alternative method to sterilization. Supercritical carbon dioxide is easily available, inexpensive, non-toxic, and ensures gentle treatment of the product.

A high-throughput cloning approach that will decrease the time taken to research and develop biocatalysts. GRASP™ and meta-GRASP™ allow high throughput genome-mining to produce new and highly diverse planes of enzymes for biocatalysis. With this technology, they have designed a Biocatalysis Enzyme Toolkit. 

Synthetic biology of fine and specialty chemicals for products and intermediates in drug development, agrochemistry, and sustainable bio-manufacturing. Synbiochem uses a Design-Build-Test-Learn (D/B/T/L) pipeline in their chemical production. They design novel enzymes, pathways, and chassis; build multiple pathways in host cassis using automated assembly; test and evaluate these pathways using advanced optimized ultra high-throughput (HTP) screening and analytical methods; and learn methods to inform re-design and optimization. This pipeline allows for rapid prototyping and scalability.

Immobilization matrix for the immobilization of enzymes. Biocatalysts allow reactions with milder and safer conditions, high regioselectivity, and enantioselectivity. Enzyme immobilizations enable the recycling of enzymes, increase process efficiency, and reduce enzyme-removal steps. It also increases selectivity, stability, and activity and restricts enzyme movements, protecting the biocatalysts from harsh conditions. This product immobilizes enzymes on the surface without losing activity, facilitating the purification of the catalyst.

Develops and scales continuous processes using flow chemistry technology. Continuous flow reactors save energy through increased efficiency, development speed, selectivity, and flexibility compared to conventional batch reactors. Utilizing microreactor technology also increases efficiency by decreasing mass, heat transfer length, and reaction volume. Continuous flow reactors also require fewer operational steps, improving worker safety. 

Polyester polyols made from byproduct of the phtahlic anhydride process. Byproducts from the phthalic anhydride process are usually disposed by incineration. Using these byproducts to manufacture polyester polyols reduces waste and its associated environmental impacts.

Thermal paper free of chemical color developers that releases images from a purely physical process. This product consists of three layers: a base paper, a colored paper, and an opaque paper layer. The opaque layer is comprised of polymeric particles (opaque styrene acrylic resin hollow spheres) that hide the pigmented-colored layer. When the opaque layer is exposed to heat, it becomes transparent, creating the print by revealing the colored layer underneath.

Method for electropolishing niobium surfaces with environmentally benign electrolytes. Niobium is one of the best materials for superconductor radiofrequency cavities. Conventional methods for making the interior of niobium optimally smooth are hazardous to the environment as they use concentrated sulfuric and hydrofluoric acids. Contrarily, Faraday Technologies electropolishes niobium with the repeated use of bipolar electric fields. This process uses less concentrated sulfuric acid compared to traditional methods and eliminates hydrofluoric acid.