Catalysis plays an essential role in the synthesis of organic compounds, fully aligning with the ninth principle of sustainable chemistry. In recent years, nanomaterials have emerged as promising catalysts, offering stability, recyclability, and high efficiency. Among the most widely used catalysts in organic synthesis are those derived from palladium (Pd), a highly effective but costly and scarce metal. As a result, the development of more abundant and affordable alternatives, such as cobalt (Co), has garnered significant attention.¹ Co nanocatalysts not only overcome the economic and availability limitations of Pd but also introduce unique properties, such as magnetic behavior, which facilitates catalyst recovery and reuse. Additionally, the reduction of nitro compounds remains a pivotal reaction for obtaining amine derivatives, compounds of critical importance in both the chemical and pharmaceutical industries.¹ Herein, we present the synthesis and stabilization of Co nanoparticles (Co NPs) in natural eutectic solvents (NADEs) and evaluate their catalytic performance in the reduction of nitro compounds. Depending on their composition, NADEs demonstrated stabilizing properties for the synthesis of Co nanocatalysts, providing a greener and more efficient approach that enhances the sustainability of catalytic processes.