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Redesign of the Sertraline Production Process

New process for the manufacturing of sertraline, the active ingredient of Zoloft®. Sertraline is traditionally manufactured through a three-step streamlined process. This process is relatively wasteful and has low efficiency. Pfizer has developed a new single-step manufacturing process with environmental and human safety improvements, high yields, and an extremely pure product. Using a new palladium catalyst reduces the use of raw materials. The process has better reagents economy and improved cost-efficiency. 
Contact/Additional InfoContact through website:
https://www.pfizer.com/contact

Website:
https://www.pfizer.com/

Inventor/Owner/Manufacturer/Supplier
Pfizer
Category
References

Publications:
https://www.epa.gov/greenchemistry/presidential-green-chemistry-challenge-2002-greener-synthetic-pathways-award