Synthesis of sitagliptin for drug, Januvia. Januiva is used to treat type II diabetes. The active ingredient, sitagliptin, conventionally requires an expensive and energy intensive crystallization and high-pressure step. These companies use transaminase enzymes to increase selectivity and efficiency and reduce overall waste.
Contact/Additional InfoMerck:
Tel: 1-908-740-4000
Contact through website:
https://www.merck.com/contact-us/
Codexis:
Tel: 650-421-8100
Email: [email protected]
Websites:
https://www.merck.com/
https://www.codexis.com/
Inventor/Owner/Manufacturer/Supplier
Merck & Co., Inc.
Inventor/Owner/Manufacturer/Supplier: Other
This is Merck & Codexis. Right now, you can only add one.
Stage of Development
Category
References
Publications:
https://www.epa.gov/greenchemistry/presidential-green-chemistry-challenge-2010-greener-reaction-conditions-award