A framework for chemical hazard assessments under Safe and Sustainable by Design using multiple in silico tools
The hazard identification of chemicals is a key step of the “Safe and Sustainable by Design” (SSbD) framework introduced by the European Commission, aiming to eliminate hazardous substances early in innovation. In this context, in silico methods such as (Quantitative) Structure–Activity Relationship ((Q)SAR) models offer rapid, cost-effective, and animalfree alternatives for early-stage hazard screening. The Partnership for the Assessment of Risks from Chemicals (PARC) is developing a toolbox to facilitate SSbD assessments containing numerous (Q)SAR models.
