Given the importance of solvents to process mass intensity, solvent selection has been an area of intense interest to ACS GCI Pharmaceutical Roundtable member companies. While there are a variety of solvent selection tools available, this is the first tool that has been developed by practicing pharmaceutical process development experts. This interactive tool enables you to select solvents based upon a variety of key solvent properties. Solvents which are close to each other in the principal components (PCA) map have similar properties, whereas distant solvents are significantly different. The tool enables you to download solvent property information such as physical properties, environmental, safety, and health data, etc. Originally developed by AstraZeneca, this tool was recreated for public access by the ACS GCI Pharmaceutical Roundtable.
Guidance related to the Solvent Selection Guide