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Chemistry

Innovative Uses of Cassava Startch Waste from Jamaican Agro-Processors

Cassava (Manihot esculenta) also known as tapioca, is a key agricultural crop in Jamaica, valued for its potential in value-added products like known as  Bammy, Pancake Mix, Cassava Chips, and Bammy Sticks. However, the production of these items generates significant waste, including peelings (20-30% of the tuber weight), fibrous by-products (pulp waste), starch residue, and wastewater.

From the Computer to the Lab: Rational Design and Synthesis of Light-Emitting Materials

Many organic molecules are efficient light emitters used for optoelectronic devices such as OLEDs, due to their advantages over metallic counterparts, including lower toxicity, simpler disposal, and sustainability. However, the methodologies commonly used in organic synthesis to obtain these molecules often rely on harsh conditions and generate large amounts of waste, making them both ineffective and inefficient. This work aligns with some of the principles of green chemistry across different stages.

Leveraging Templated Growth Technique to Synthesize Cu Based Metastable, Bimetallic Phosphide Nanoparticles

The existing global energy crisis demands potential materials for applications relating to renewable energy production, for instance, hydrogen fuel generation via water splitting. Transition metal phosphide (TMP) nanoparticles e.g., copper phosphide (Cu3-xP), nickel phosphide (Ni2P), etc. are well known water splitting catalysts. Our prior experiences with TMPs confirm the superior activity of bimetallic phosphides over their monometallic counterparts.

Utilizing Silicon Chemistry: A Greener Approach for Achieving Regioselective Wittig Rearrangements and [1,2]-Carbon to Carbon Silyl Migration

The Wittig rearrangements ([2,3], [1,2] and [1,4]) are a pivotal synthetic strategy for forming carbon-carbon bonds. Despite extensive documentation of the [2,3]-Wittig, the questions related to the regioselective pathways of the [1,2] and [1,4]-Wittig rearrangements remain unanswered. Furthermore, it is unclear whether the [1,4]-Wittig occurs via a concerted or stepwise mechanism is unclear. The [1,4]-Wittig also has a limited substrate scope.

Growth of AgSbS2 Single Crystals for Radiation Detector Applications

In medical imaging, nuclear safety, intelligence, and security applications, there is a high demand for room-temperature radiation detectors. A desirable radiation detection material must exhibit high sensitivity to radiation, high density, and a suitable band gap. Silver antimony sulfide (AgSbS₂) is an emerging ternary semiconductor material with potential applications in photovoltaics, optoelectronics, and radiation detection.

Development of Sustainable Water-Based Multifunctional Nanofluid with Xanthan Gum (XG) and Graphene Oxide

The exploration of oil in ultra-deep waters (offshore) is crucial due to the high demand for this resource. However, challenges, like the complex task of drilling through salt layers and stringent environmental concerns persist. Drilling fluid plays a fundamental role in the well drilling process, aiding in drill cooling, gravel transportation, and other functions. Although water-based fluids are preferable environmentally, they tend to be less efficient and degrade under high pressures and temperatures.

Synthesis of Alkyne-Functionalized Cellulose for Attachment of (Bio)molecules via Click Reaction

The development of sustainable and environmentally friendly materials is a key component of the green chemistry concept. In this context, cellulose tosylate (MCC-Tos) serves as a versatile precursor for the functionalization of cellulose. By substituting tosyl groups with alkyne groups, the potential of cellulose is enhanced, making it compatible with click chemistry reactions such as thiol-yne and copper-catalyzed alkyne-azide cycloaddition (CuAAC), which promotes greener processes.

NMR-based Metabolomics Study of Kidney (HEK 293T) Cells Cultured on SAM Coated Indium Tin Oxide (ITO) Glass Substrates

The use of glass substrates to enhance cellular adhesion exemplifies the principles of green and sustainable chemistry in practice. Upcycling waste glass into a valuable resource mitigates environmental pollution, promotes innovation, and conserves resources. The Human embryonic kidney293T (HEK293T) cells have been used in organoid formation and specialized applications within organoid systems; however, they often suffer from loose adherence, which limits their applicability.

Designing CO2-responsive and Degradable Polymers

Plastic is a frequently used material that can vastly harm the environment. Most disposed plastics persist in the environment, breaking down into smaller particles known as microplastics that harm aquatic life and humans. Polymers capable of degradation can alleviate the presence of microplastics in the environment, but degradation rates are often slow (>100 years) and harsh acidic or basic conditions may be required for complete degradation. 

Bioguided Fractionation of Modified Plant Extract: An Efficient Approach for Discovering Bioactive Compounds and Identifying Biological Targets

This study presents a methodology for bioactivity-guided fractionation of chemically modified Ambrosia tenuifolia extracts using mild derivatization conditions at room temperature. New trypanocidal compounds less toxic than the starting materials were obtained in a single reaction step. In addition, bioinformatics tools were used to identify potential biological targets for Trypanosoma cruzi, reducing the need for extensive biological testing.