Design of Safer Chemicals

The Need for Safer Chemistry in Beauty: Opportunities for Innovation

In this report, major safer chemistry challenges and solutions in ingredients and materials across the beauty and personal care industry are highlighted.  Specific needs for new ingredients and materials are highlighted, and a snapshot of innovative safer chemistry companies developing promising new materials is provided. The report also highlights evolving brands and retailers standards for safety and sustainability that move the industry forward.

Guidance on Key Considerations for the Identification and Selection of Safer Chemical Alternatives

This guidance was developed with the aim to advance broader agreement on a general approach and criteria for the selection of safer alternatives, with a focus on chemical substitution. It is intended to advance a consistent understanding of the minimum requirements needed to determine whether a chemical alternative is safer than the priority chemical, product, or technology for substitution, independent of the entity performing the assessment or the alternatives assessment framework being used. 

Safe-and-sustainable-by-design approach to polyesters from non-oestrogenic bisphenols

Most contemporary chemical processes rely on non-renewable resources and reagents associated with negative impact on environment and human health. As a result, the safe-and-sustainable-by-design (SSbD) framework is launched to guide the innovation towards safe and sustainable materials and chemical products. Bisphenol A (BPA) is a widely used chemical in the production of plastics but known to activate oestrogen receptors and linked by numerous studies to adverse effects on both human health and the environment.

Synthesis of bioactive molecules from 5-hydroxymethylfurfural vía Passerini multicomponent reaction (ACS Green and Sustainable Chemistry Summer School, GSCSS - 2024)

The pharmaceutical industry is currently experiencing increasing demand for small-molecule drugs. However, a significant portion of the raw materials used in drug production are fossil-based, originating from crude oil. This reliance on non-renewable resources presents major challenges, particularly in the context of global environmental crises such as climate change, greenhouse gas emissions, and dwindling oil reserves.