ecotoxicology

The IC2 developed the Chemical Hazard Assessment Database (CHAD) to enable users to search for free publicly available GreenScreen® assessments. The purpose of this tool is to promote awareness of assessments conducted on chemicals of high concern as well as potential alternatives, facilitate transparency and discussion, and reduce duplication of effort. 

The Open (Quantitative) Structure-activity/property Relationship App (OPERA) is a free and open-source/open-data suite of QSAR models providing predictions for toxicity endpoints and physicochemical, environmental fate, and ADME properties. OPERA was created in alignment with rigorous OECD standards to provide a regulatory-oriented alternative to experimental measurements. All OPERA models were built on curated data and QSAR-ready chemical structures standardized using an open-source workflow implemented in the application. Models are explained in the 2018 publication by Mansouri et.

ECOTOX is a comprehensive Knowledgebase providing single chemical environmental toxicity data on aquatic and terrestrial species.

Managed by ChemFORWARD, the data trust is designed to simplify access to chemical hazard data from dozens of credible sources, curate, maintain and continuously improve the data, and harmonize the information for actionable decision support that will accelerate the global transition to safer chemistry. 

The data trust is populated and continually updated by licensed toxicologists using a comprehensive, globally accepted methodology. Each CHA is peer reviewed by independent toxicologists before being posted.