Synthetic

Plastic-Free, Biodegradable, Non-Toxic, Sustainable Materials

Plant-based materials developed by Natural Fiber Welding (NFW) that eliminates the use of synthetic toxins or plastics at any stage of manufacturing. Natural ingredients such as natural rubber, recycled cotton, recycled Mirum®, hemp, coconut husks, structural colorant, and cork are shaped and molded at the molecular level previously only achieved with synthetic materials to create products for fashion, footwear, accessories, and automotive industries. NFW currently offers four bio-based, low-carbon materials.

Progress towards a more sustainable synthetic pathway to ibuprofen through the use of solar heating

Ibuprofen is a nonsteroidal anti-inflammatory drug that is commonly used worldwide for pain relief and fever/inflammation reduction. It was discovered in the 1960s by Andrew Dunlop, who initially tested the drug on cures for hangovers. The drug was first made available via prescription in 1974 (United States) and soon became available as an over the counter drug purchasable at retail shops around the globe.

Manufacturing Process for Zerbaxa™

Merck Research Laboratories redesigned the manufacturing process for Zerbaxa™, a drug used to treat gram-negative bacterial infections resistant to conventional antibiotics. Ceftolozane sulfate is a key ingredient of the drug. Unfortunately, existing processes for its production require hazardous chemicals, a high process mass index, long cycle times, and low yields. Merck developed a sustainable second-generation manufacturing route.

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