green chemistry

Enhancing the efficiency of material processing, utilization, and recycling is pivotal for advancing sustainability in modern society. The objective of this study is to create sustainable methods for converting non-food biomass into recyclable polymers. One key compound, 4,4'-biphenyldicarboxylic acid (BPDA), is used as an additive in copolymer production and as a blending agent to improve the properties of polyester. BPDA was synthesized through the oxidation of 4,4'-dimethylbiphenyl (DMBP), a compound that can be efficiently derived from biomass-sourced 2-methylfuran.

Supported metallic and bimetallic nanocatalysts were synthesized and characterized. They were employed in different steps of the synthesis of a variety of bioactive compounds, taken in place the high atom economy and the sustainability of the process. The recoverability and reusability of the nanocatalysts was studied. The nanocatalyst were used particularly in C-H activation reaction, through a cross dehydrogenative coupling reaction (CDC), to form new C-C and C-heteroatom bonds.

Sulfonamides represent an important family of compounds with diverse biological activities, especially recognized as antibiotics. 1,2,4-Benzothiadicines-1,1-dioxide belong to a family of cyclic sulfonamides with significant pharmacological applications, such as antimicrobial, antiviral and antidiabetic. In addition, they are used clinically as diuretics and antihypertensives.

Heterocyclic ring systems are essential in drug design, serving as core structures in many approved drugs. Nitrogen- and oxygen-containing heterocycles, in particular, have become increasingly significant in recent years. Despite the availability of efficient synthetic methods, there is an ongoing need for new approaches that offer higher molecular complexity, better functional group compatibility, and atom economy, using readily available starting materials under mild conditions.